Roche partners with Janus to develop treatment for autoimmune disease
US biotechnology firm Janus Biotherapeutics said it has partnered with Swiss drug major Roche (ROG: SIX) to develop a toll-like receptor (TLR) inhibitor with the potential to treat several autoimmune diseases. If successful, the deal also provides for Roche to acquire US-based Janus.
Under the terms of the agreement, Janus will receive an undisclosed upfront cash payment and R&D funding over a collaboration period.
TLRs are an important class of proteins that play a key role in the innate immune system. Strong scientific evidence links aberrant TLR activation and signalling with the development of autoimmune disorders. Janus will work exclusively with Roche on TLR research and development.
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