Roche partners with Janus to develop treatment for autoimmune disease

21 August 2015

US biotechnology firm Janus Biotherapeutics said it has partnered with Swiss drug major Roche (ROG: SIX) to develop a toll-like receptor (TLR) inhibitor with the potential to treat several autoimmune diseases. If successful, the deal also provides for Roche to acquire US-based Janus.

Under the terms of the agreement, Janus will receive an undisclosed upfront cash payment and R&D funding over a collaboration period.

TLRs are an important class of proteins that play a key role in the innate immune system. Strong scientific evidence links aberrant TLR activation and signalling with the development of autoimmune disorders. Janus will work exclusively with Roche on TLR research and development.

This article is accessible to registered users, to continue reading please register for free. A free trial will give you access to exclusive features, interviews, round-ups and commentary from the sharpest minds in the pharmaceutical and biotechnology space for a week. If you are already a registered user please login. If your trial has come to an end, you can subscribe here.

Try before you buy

Free

7 day trial access

Take a Free Trial

All the news that moves the needle in pharma and biotech
Exclusive features, podcasts, interviews, data analyses and commentary from our global network of life sciences reporters.
Receive The Pharma Letter daily news bulletin, free forever.

Become a subscriber

£820

Or £77 per month

Subscribe Now

Unfettered access to industry-leading news, commentary and analysis in pharma and biotech.
Updates from clinical trials, conferences, M&A, licensing, financing, regulation, patents & legal, executive appointments, commercial strategy and financial results.
Daily roundup of key events in pharma and biotech.
Monthly in-depth briefings on Boardroom appointments and M&A news.
Choose from a cost-effective annual package or a flexible monthly subscription

The Pharma Letter is an extremely useful and valuable Life Sciences service that brings together a daily update on performance people and products. It’s part of the key information for keeping me informed

Chairman, Sanofi Aventis UK