Rexgenero's Phase III cell therapy trials enter critical phase

24 April 2019
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Privately-owned UK-based regenerative medicine company Rexgenero has provided an update on its Phase III studies of REX-001 to treat critical limb ischemia (CLI) in diabetes.

The autologous cell therapy is now being tested at 12 of 25 planned trial sites across Europe, with additional hospitals expected to be initiated by the end of the year.

REX-001 consists of bone marrow-derived white blood cells extracted from the patient and has shown efficacy in 80% of patients in Phase II and I/II studies. Rexgenero is planning to treat 138 patients in the two SALAMANDER trials.

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