Retrospective analysis shows tumor shrinkage with Amgen's talimogene laherparepvec

16 March 2014

Leading independent biotech firm Amgen (Nasdaq: AMGN) says that findings from a pre-specified retrospective analysis of patients with metastatic melanoma that showed talimogene laherparepvec reduced the size of injected tumors and also non-injected tumors that had metastasized to other parts of the body.

The analysis recorded tumor-level responses from a pivotal Phase III study evaluating talimogene laherparepvec in patients with injectable unresected stage IIIB, IIIC or IV melanoma compared to granulocyte-macrophage colony-stimulating factor (GM-CSF). Full results were presented last week during an oral session at the Society of Surgical Oncology (SSO) 67th Annual Cancer Symposium in Phoenix.

Talimogene laherparepvec is an investigational oncolytic immunotherapy designed to selectively replicate in tumor tissue and to initiate a systemic anti-tumor immune response.

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