Repatha reduces risk of cardiovascular events, study shows

3 February 2017

US biotech major Amgen (Nasdaq: AMGN) has announced that its trial on whether the cholesterol-lowering drug Repatha (evolocumab) reduces the risk of cardiovascular events in patients with clinically evident atherosclerotic cardiovascular disease (ASCVD) has met its primary composite endpoint.

This endpoint measured the time to cardiovascular death, myocardial infarction, stroke, hospitalization for unstable angina, or coronary revascularization, comparing Repatha in combination with statin therapy to placebo plus statin therapy.

The key secondary endpoint in the Fourier trial was also met, measuring the time to cardiovascular death, myocardial infarction or stroke.

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