PureTech acquires LYT-100 to treat lymphedema

17 July 2019
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UK biopharma company PureTech Health (LSE: PRTC) today announced it has acquired and plans to develop a clinical-stage product candidate for the potential treatment of lymphatic and immunofibrotic diseases, including lymphedema.

No financial terms of the deal were disclosed, as was not the source of the candidate, but PureTech’s shares dipped 2% on the news this morning.

In preclinical studies, the oral, small molecule candidate, LYT-100, demonstrated anti-fibrotic and anti-inflammatory mechanisms, and in a Phase I clinical trial in healthy volunteers, LYT-100 was observed to be well tolerated with a favorable pharmacokinetic profile to support twice daily oral dosing.

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