Prothena targets new class of treatment for rare disease

30 June 2023

Dublin, Ireland-headquartered protein specialist Prothena (Nasdaq: PRTA) has published results from the Phase III VITAL trial in a journal of the American Society of Hematology (ASH).

A post hoc analysis of certain people with AL amyloidosis shows a statistically-significant survival benefit of 74% for those treated with birtamimab, an antibody designed to clear the dysregulated proteins that are a hallmark of the condition.

People in the trial were given standard of care and either birtamimab or a placebo, with the latter cohort achieving a 49% survival benefit.

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