ProQR defends its Axiomer IP portfolio from new challenge

19 April 2024

Dutch rare diseases biotech firm ProQR Therapeutics (Nasdaq: PRQR) saw its shares leap more than 11% to $2.07 today, after it announced its successful defense against opposition filed against a key patent for its ADAR-mediated RNA editing platform Axiomer.

ProQR explained that the opposition was filed in June 2021 with the European Patent Office (EPO) by a strawman against ProQR’s granted patent EP 3 507 366 B1, which relates to editing oligonucleotides that have certain chemical modifications in the base and/or ribose sugar to increase stability and recruit endogenous ADAR to edit the target adenosine.

The Opposition Division of the EPO held a public hearing on April 17, 2024, and ruled such that ProQR’s strong IP position on chemically modified editing oligonucleotides was maintained.

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