Preliminary Moderna booster data offers hope amid Omicron surge

21 December 2021

US biotech Moderna (Nasdaq: MRNA) has announced preliminary neutralizing antibody data against the Omicron variant following the company’s booster candidates at 50µg and 100µg dose levels.

The currently authorized 50µg booster of mRNA-1273, or Spikevax, increased neutralizing antibody levels against Omicron approximately 37-fold compared to pre-boost levels, while a 100µg dose of mRNA-1273 increased neutralizing antibody levels approximately 83-fold compared to pre-boost levels.

"Moderna will continue to rapidly advance an Omicron-specific booster candidate into clinical testing"Stéphane Bancel, chief executive of Moderna, said: “The dramatic increase in COVID-19 cases from the Omicron variant is concerning to all. However, these data showing that the currently authorized Moderna COVID-19 booster can boost neutralizing antibody levels 37-fold higher than pre-boost levels are reassuring.

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