Prana pairs up with Takeda in Parkinson's gastrointestinal neuropathology
Australia’s Prana Biotechnology (Nasdaq: PRAN) was trading 6% higher at $2.80 late morning on Tuesday after the announcement of a research collaboration with Takeda Pharmaceutical (TYO: 4502), Japan’s largest drugmaker.
The companies will jointly study the ability of Prana’s investigational movement disorders compound, PBT434, to slow or prevent neurodegeneration of the gastrointestinal system, one of the important non-motor features of Parkinson’s disease.
Parkinson’s disease is characterized by the loss of neurons and their networks in the brain and in the gut. The cause of neurodegeneration and gastrointestinal dysfunction in Parkinson’s disease is not known, but the protein alpha-synuclein has been hypothesized to be implicated in this process.
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