Danish biotech company Genmab (OMX: GEN) has released positive top-line data on its daratumumab in the treatment of multiple myeloma, resulting in the firm’s shares rising 3.7% to 890.50 Danish kroner in early trading.
The drug is being co-developed with Janssen-Cilag, a subsidiary of US health care giant Johnson & Johnson (NYSE: JNJ), to which Genmab granted an exclusive worldwide license for daratumumab in August 2012.
Genmab announced today that the Phase III Castor study (MMY3004) of daratumumab in combination with bortezomib and dexamethasone versus bortezomib and dexamethasone in patients with relapsed or refractory multiple myeloma met the primary endpoint of improving progression free survival (PFS) in an interim analysis (p =< 0.0001). The planned interim analysis was conducted by an Independent Data Monitoring Committee (IDMC).
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