Pivotal data and $150 million fundraising bring Autolus BLA into sight

9 December 2022

UK biotech Autolus Therapeutics (Nasdaq: AUTL) has announced that the pivotal Phase II FELIX trial of obecabtagene autoleucel (obe-cel) in relapsed/refractory (r/r) adult acute lymphoblastic leukemia (ALL) has met its primary endpoint at interim analysis.

The CD19 CAR T-cell therapy obe-cel demonstrated an overall remission rate of 70% in the interim analysis of 50 patients.

"Obe-cel’s high level of anti-leukemia activity combined with a well manageable tolerability profile is a significant step forward in this underserved disease setting"

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