Pivlaz reaches end of long research road with launch in Japan

20 April 2022

The Japanese business of Swiss biotech Idorsia (SIX: IDIA) has launched Pivlaz (clazosentan), a potent, selective endothelin A (ETA) receptor antagonist which targets the root cause of cerebral vasospasm.

The product was approved in Japan in January 2022, based on a dedicated Phase III program conducted in the country.

Under development for many years, the approval of Pivlaz has been a long time coming, with Phase III failures as far back as 2010 challenging the prospects for what was then an Actelion candidate.

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