UK pharma major GSK’s (LSE: GSK) shares were down 4.3% at 1,383.60 pence by early afternoon today, as it announced disappointing Phase III results with its Blenrep (belantamab mafodotin).
The company revealed that Blenrep monotherapy versus pomalidomide in combination with low dose dexamethasone (PomDex) in patients with relapsed or refractory multiple myeloma (RRMM) did not meet its primary endpoint of progression-free survival (PFS), denting hopes the company can move it up to earlier lines of treatment.
Data from the so-called superiority trial dubbed DREAMM-3 may call into question Blenrep's existing approval, according to JP Morgan analysts, who noted that many regulatory scenarios now exist, including existing approvals being rescinded or authorities waiting for further data.
This article is accessible to registered users, to continue reading please register for free. A free trial will give you access to exclusive features, interviews, round-ups and commentary from the sharpest minds in the pharmaceutical and biotechnology space for a week. If you are already a registered user please login. If your trial has come to an end, you can subscribe here.
Login to your accountTry before you buy
7 day trial access
Become a subscriber
Or £77 per month
The Pharma Letter is an extremely useful and valuable Life Sciences service that brings together a daily update on performance people and products. It’s part of the key information for keeping me informed
Chairman, Sanofi Aventis UK
Copyright © The Pharma Letter 2024 | Headless Content Management with Blaze