Phase III success for new targeted breast cancer therapy

5 December 2023

Swiss pharma giant Roche (ROG: SIX) has announced positive results from the Phase III INAVO120 study of its investigational breast cancer therapy, inavolisib.

The trial is testing the drug, a small molecule which targets the PIK3CA-mutation, in combination with Pfizer’s (NYSE: PFE) Ibrance (palbociclib), plus fulvestrant, marketed by AstraZeneca (LSE: AZN) under the Faslodex brand.

Roche is looking to offer the combination treatment in the first-line setting, for certain people with locally advanced or metastatic breast cancer.

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