Phase III failure for Imfinzi in non-small cell lung cancer

19 December 2022

AstraZeneca (LSE: AZN) has reported negative results from the Phase III PEARL study of Imfinzi (durvalumab) in lung cancer.

The results show the trial did not achieve statistical significance for the primary endpoint of improving overall survival (OS), versus platinum-based chemotherapy.

The British pharma major is testing the checkpoint blocker as a monotherapy treatment of people with metastatic non-small cell lung cancer (NSCLC).

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