Phase I result shows promise of natural killers in blood cancer

6 December 2022

While autologous CAR-T cell therapies have upended the treatment landscape for people with blood cancer, associated toxicities have limited access for many people.

Now, a new off-the-shelf natural killer cell approach to tackling cancer hopes to match the impressive efficacy of CAR-T cell treatments in lymphoma, while improving on safety.

A Phase I update from Californian immuno-oncology firm Nkarta (Nasdaq: NKTX) shows that 70% of patients in the dose escalation study showed a complete response to its CAR-NK cell therapy, NKX019.

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