Pfizer expands anti-infectives pipeline with acquisition

29 April 2021

US pharma giant Pfizer (NYSE: PFE) said yesterday that it has acquired San Diego-based Amplyx Pharmaceuticals, a privately-held biotech dedicated to the development of therapies for debilitating and life-threatening diseases that affect people with compromised immune systems.

Amplyx’ lead compound, fosmanogepix (APX001), is a novel investigational asset under development for the treatment of invasive fungal infections. Financial terms of this acquisition were not disclosed.

In addition to fosmanogepix, Pfizer acquires Amplyx' early-stage pipeline, including potential antiviral (MAU868) and antifungal (APX2039) therapies. MAU868, licensed from Novartis (NOVN: VX), is a potent neutralizing monoclonal antibody with activity against the BK virus.

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