Pfizer and BioNTech begin study of enhanced COVID-19 mRNA-based vaccine

27 July 2022

US pharma giant Pfizer (NYSE: PFE) and Germany’s BioNTech (Nasdaq: BNTX), the partnership that brought the world Comirnaty (pictured), one of the first effective COVID-19 vaccines, is at it again.

The companies have launched a Phase II study to evaluate the safety, tolerability, and immune response of an enhanced COVID-19 mRNA-based vaccine candidate at a 30µg dose level.

This bivalent COVID-19 vaccine candidate, BNT162b5, consists of RNAs encoding enhanced prefusion spike proteins for the SARS-CoV-2 ancestral strain and an Omicron variant.

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