Pfizer and Astellas' Xtandi fails in late-stage cancer trial v Zytiga
US pharma giant Pfizer (NYSE:PFE) and Japan's Astellas (TSE:4503) have announced that treatment with Xtandi (enzalutamide), plus Zytiga (abiraterone acetate) and the steroid treatment prednisone failed to best treatment with the latter two drugs alone in a Phase IV PLATO trial in extending progression-free survival in prostate cancer patients.
The drug was tested in addition to the steroid, plus Johnson & Johnson's (NYSE: JNJ) Zytiga in 509 sufferers of metastatic castration-resistant prostate cancer (CRPC) who had not received chemotherapy. The patients were previously treated with Xtandi until their cancer progressed.
"We are committed to continuing to explore the clinical potential of Xtandi across the disease continuum"
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