Patisiran a launching pad for Alnylam venture into NASH research

23 March 2018

Regeneron Pharmaceuticals (Nasdaq: REGN) and Alnylam Pharmaceuticals (Nasdaq: ALNY) will collaborate to identify RNAi therapeutics for non-alcoholic steatohepatitis (NASH) and potentially other related diseases.

The partnership is based on work done by Regeneron around a variant in the HSD17B13 gene, which is associated with a reduced risk of chronic liver diseases.

RNA interference (RNAi) is a natural cellular process of gene silencing, an approach led by Alnylam for a number of years, but one which has yet to yield any approved therapies.

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