Otsuka inks deal for rights to migraine drug candidate fremanezumab

17 May 2017

Japan’s Otsuka Pharmaceutical (TYO: 4578) has signed a deal to acquire rights to the investigational drug candidate fremanezumab (TEV-48125).

The drug is an anti-calcitonin gene-related peptide (CGRP) monoclonal antibody for the prevention of migraine, under development by Israel’s Teva Pharmaceutical Industries (NYSE: TEVA). Through the agreement, Otsuka secures exclusive rights in Japan to fremanezumab, which Teva is globally developing in other countries.

The annual prevalence of migraine in Japan is 8.4% of adults and around 8.4 million patients suffer from the condition. The highest prevalence rate is among young women, with about 20% of cases reported among women in their 30s. Acute as well as preventive treatments exist for migraine, but there is an unmet need for targeted, preventive therapies, noted Teva.

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