Opdivo plus Yervoy given concomitantly with chemo showed improved survival in NSCLC

14 May 2020
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Ahead of featuring the data at the American Society of Clinical Oncology (ASCO) meeting later this month, results from the Phase III CheckMate-9LA trial, which demonstrated a statistically-significant and clinically-meaningful survival benefit with Opdivo (nivolumab) plus Yervoy (ipilimumab), given concomitantly with two cycles of chemotherapy, for the first-line treatment of metastatic non-small cell lung cancer (NSCLC), were released today by Bristol-Myers Squibb (NYSE: BMY).

The study met both its primary and key secondary endpoints, demonstrating superior overall survival (OS), progression-free survival (PFS) and overall response rate (ORR) for the dual immunotherapy plus chemotherapy combination versus chemotherapy alone.

Death risk reduced 31% vs chemo alone, and 38% in patients with PD-L1

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