Ono's new CAR-T partner must be Fate

18 September 2018

Japanese drugmaker Ono Pharmaceutical (TYO: 4528) and US biotech Fate Therapeutics (Nasdaq: FATE) have signed a deal to develop and commercialize two off-the-shelf CAR-T therapies for cancer.

The companies will advance each candidate to a pre-definied preclinical milestone. The first targets an antigen expressed on certain lymphoblastic leukemias, with Fate retaining global responsibility for development and commercialization and Ono having the option to assume responsibilities in Asia.

The second candidate targets a new antigen, identified by Ono, expressed on certain solid tumors. The Osaka-based company this time retains rights except that Fate can co-develop and co-commercialize the product in the USA and Europe.

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