Ono closer to Fate after exercising CAR-T option

8 November 2022

Japan’s Ono Pharmaceutical (TYO: 4528) has exercised its option to an iPS cell-derived chimeric antigen receptor (CAR)-T cell therapy targeting human epidermal growth factor receptor 2 (HER2)-expressing solid tumors, under its collaboration with Fate Therapeutics (Nasdaq: FATE).

The companies entered into the deal for the product candidate, named ONO-8250/FT825, in September 2018.

"The goal of submitting an IND to US Food and Drug Administration in 2023"

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