Off-the-shelf T-cell specialist hits buffers with mid-stage flop
A Phase II failure for Californian cell therapy company Atara Biotherapeutics (Nasdaq: ATRA) has prompted a share sell-off, with the company’s stock falling 80% in value on Thursday.
The immunotherapy specialist is using its novel allogeneic Epstein-Barr virus (EBV) T-cell platform to develop therapies for people with cancer and autoimmune diseases.
Primary analysis data show that the Phase II EMBOLD study of ATA188 did not meet its primary endpoint, with fluid and imaging biomarkers also failing to provide evidence of efficacy.
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