Novo Nordisk sells rights to antiC5aR antibody for 410 million euros

3 June 2017

Shares of Novo Nordisk (NOV: N) rose 2.5% to 291.50 Danish kroner yesterday, after it was revealed that the Danish diabetes care giant had out-licensed full worldwide exclusive rights to develop and commercialize a first-in-class clinical-stage anti-C5aR antibody (IPH5401) representing a novel therapeutic approach in immuno-oncology, to French drugmaker Innate Pharma (Euronext Paris: IPH).

IPH5401 is a strategic fit to Innate Pharma current immuno-oncology pipeline, the Frenhc firm said. It adds a clinical-stage proprietary product that reinforces Innate Pharma’s position in the field of antibodies targeting the tumor microenvironment beyond the company’s activities in the adenosine pathway. Innate Pharma plans to start trials with IPH5401 in oncology in 2018.

Novo Nordisk has conducted two Phase I trials with anti-C5aR in patients with rheumatoid arthritis, where a good safety profile was demonstrated.

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