Novartis says Phase III APPOINT-PNH trial shows iptacopan improves hemoglobin
With another set of strong data under its belt, Swiss pharma giant Novartis (NOVN: VX) is now looking to filing regulatory applications for its investigational oral monotherapy iptacopan.
Novartis today announced detailed results from the Phase III APPOINT-PNH trial of iptacopan in complement-inhibitor-naïve (including anti-C5 therapies) adults with paroxysmal nocturnal hemoglobinuria (PNH).
According to Evaluate analysts, iptacopan, which is also being tested in other indications, has been projected to have net present value of $4.1 billion for the company.
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