NICE U-turn on Roche's blood cancer drug Gazyvaro

12 February 2018
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In a reversal of the medicines cost-effectiveness watchdog for England and Wales’ initial Appraisal Consultation Document, the National Institute for Health and Care Excellence (NICE) has today issued its final decision regarding the blood cancer drug Gazyvaro (obinutuzumab).

It recommends that Gazyvaro, from Swiss pharma giant Roche (ROG: SIX), is made routinely available in combination with chemotherapy followed by obinutuzumab maintenance for the treatment of patients with previously untreated advanced follicular lymphoma (FL) who are at higher risk of relapse (patients with a Follicular Lymphoma Prognostic Index (FLIPI) score of 2 or more).

The list price of the drug is £3,312 ($4,574) per 1,000mg vial (excluding VAT; British national formulary [BNF] online, August 2017).

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