NICE recommendation for Chiesi's Lamzede

9 November 2023
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The National Institute for Health and Care Excellence (NICE) has recommended Lamzede (velmanase alfa) in its final evaluation document as an option for treating the non-neurological signs and symptoms of mild to moderate alpha-mannosidosis in England and Wales.

Chiesi’s product has become the first and only enzyme replacement therapy recommended for use on the National Health Service (NHS) for alpha-mannosidosis, and is given to patients once-a-week by intravenous infusion.

Alpha-mannosidosis is an extremely rare, genetic condition. It is thought to affect around 25 people in England, with many of these children and young people.

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