NICE opens consultation on Millennium's Crohn's drug Entyvio

23 December 2014

In draft guidance issued today, UK health costs watchdog the National Institute for Health and Care Excellence (NICE) has not recommended Millennium Pharmaceuticals’ Entyvio (vedolizumab) to treat people with Crohn’s disease after deciding that the evidence for the drug is too uncertain.

The committee also found the drug was not likely to represent good value for the NHS. Millennium is a wholly-owned subsidiary of Japan’s largest drugmaker Takeda Pharmaceutical (TYO: 4502), which just last month received a positive provisional recommendation for Entyvio for maintenance therapy in ulcerative colitis (The Pharma Letter November 26).

Insufficient comparative data

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