Following its acceptance in the UK’s Cancer Drug Fund in October, the medicines cost-effectiveness watchdog has now agreed to the regular NHS England funding of Yescarta (axicabtagene ciloleucel).
Today, the National Institute for Health and Care Excellence (NICE) has issued a positive final appraisal determination (FAD) recommendation for Yescarta, a new type of personalized cell therapy (CAR T) manufactured by Kite, a Gilead Sciences (Nasdaq: GILD) company which re-engineers a patient’s own immune cells to fight cancer.
This is the first time that adult patients living with aggressive forms of non-Hodgkin lymphoma (NHL), such as relapsed or refractory diffuse large B-cell lymphoma or primary mediastinal large B-cell lymphoma, will be able to access a CAR T therapy in the UK. In many cases, these patients have run out of treatment options and are unlikely to survive the next six months.
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