NICE issues negative appraisal for Roche's Cotellic with Zelboraf

16 June 2016

The National Institute for Health and Care Excellence (NICE), the medicines cost-effectiveness watchdog for England, has today published draft guidance on Cotellic (cobimetinib) with Zelboraf (vemurafenib) – both from Swiss pharma giant Roche (ROG: SIX) for a type of advanced skin cancer.

The NICE does not recommend cobimetinib with vemurafenib for people with advanced BRAF V600 mutation-positive melanoma that has spread and can’t be surgically removed.

Too expensive compared to alternative treatments

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