NICE draft guidance rejects Celgene drug for MM

11 November 2016
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The National Institute for Health and Care Excellence (NICE) has today issued draft guidance rejecting use on the National Health Service of a treatment for multiple myeloma.

The cost effectiveness watchdog for England and Wales says it is not recommending US biotech firm Celgene’s (Nasdaq: CELG) Revlimid (lenalidomide) for people with multiple myelomawho have had one prior treatment with bortezomib, pointing out that it has already recommends lenalidomide as third line treatment for multiple myeloma.

Lenalidomide, for this appraisal, is used to treat people who have had one prior treatment with bortezomib and can’t have a stem cell transplant. Compared with other treatments, such as melphalan (a cytotoxic chemotherapy), the NICE appraisal committee concluded that lenalidomide, to treat multiple myeloma for this patient population, ie, earlier in the treatment pathway, is not a cost effective use of NHS resources.

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