NICE draft guidance recommends Otezla for treating psoriatic arthritis

11 October 2016

The medicines cost-effectiveness watchdog for England and Wales has today published draft updated guidance recommending National Health Service use of US biotech firm Celgene’s (Nasdaq: CELG) Otezla (apremilast) for psoriatic arthritis.

This appraisal was a rapid review of the National Institute for Health and Care Excellence (NICE) technology appraisal guidance published in December 2015. It focused on cost-effectiveness analyses using a patient access scheme agreement, which provides apremilast at a reduced cost. The discount is commercial in confidence.

The appraisal committee noted that the base-case incremental cost-effectiveness ratio (ICER) with the patient access scheme was £39,052 ($48,659) saved per quality-adjusted life-year (QALY) lost. All exploratory analyses presented by both the company and the ERG also showed that using apremilast resulted in cost savings but a QALY loss.

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