UK medicines cost-effectiveness watchdog the National Institute for Health and Care Excellence (NICE) final draft guidance recommends the use of blood cancer drug Gazyvaro (obinutuzumab) with bendamustine for use within the Cancer Drugs Fund (CDF).
The drug combination from Swiss pharma giant Roche (ROG: SIX), also known as O-Benda+O, is used to treat some people with follicular lymphoma, a rare type of non-Hodgkin lymphoma. It is used to treat these people if their disease has not responded to or has progressed during or up to six months after treatment with rituximab, either or its own or in combination with chemotherapy.
The NICE appraisal committee concluded that O-Benda+O is clinically effective, but were uncertain of its overall survival gain. Therefore, the committee recommended its use in the CDF while further evidence is collected.
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