The price of cystic fibrosis (CF) drugs developed by Vertex Pharmaceuticals (Nasdaq: VRTX) is again in the spotlight after a patient group hit out at an influential report claiming that they were not cost-effective.
The Institute for Clinical and Economic Review on Thursday released its evidence report assessing the comparative clinical effectiveness and value of cystic fibrosis transmembrane conductance regulator (CFTR) modulators, including combination therapies Symdeko (tezacaftor/ivacaftor) and Orkambi (lumacaftor/ivacaftor), as well as the monotherapy Kalydeco (ivacaftor).
"Analysis suggested that discounts of up to 77% would be needed to bring the prices into alignment with their clinical value"
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