New triple combo to be tested against pancreatic cancer

4 March 2019
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Germany’s Merck KGaA (MRK: DE) and New York’s Pfizer (NYSE: PFE) have joined an existing clinical collaboration between BioXcel Therapeutics (Nasdaq: BTAI) and Nektar Therapeutics (Nasdaq: NKTR).

BioXcel and Nektar joined forces in 2017 to explore a novel combination of Nektar’s NKTR-214, a CD122-biased agonist, and BTI’s BXCL701, a small molecule immune-modulator, against multiple cancer types.

Merck and Pfizer will contribute the checkpoint inhibitor Bavencio (avelumab) to the mix, creating a potentially potent triple combination in pancreatic cancer.

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