New Novartis real-world data show Leqvio significantly reduces LDL-C in ASCVD patients

8 April 2024

Swiss pharma giant Novartis (NOVN: VX) on Saturday presented new real-world data on its Leqvio (inclisiran) at the 2024 American College of Cardiology's Annual Scientific Session & Expo.

The data demonstrated the early addition of twice-yearly Leqvio to maximally tolerated statin therapy, prior to guideline-recommended ezetimibe, in a real-world setting significantly reduced low-density lipoprotein cholesterol (LDL-C) in patients with atherosclerotic cardiovascular disease (ASCVD), including those with a history of an ASCVD-related event, who could not reach their goal on statin therapy alone.

Novartis obtained global rights to develop, manufacture and commercialize Leqvio under a license and collaboration agreement with US RNAi therapeutics company Alnylam Pharmaceuticals (Nasdaq: ALNY).

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