Neovii out-licenses Grafalon for China and Japan

5 July 2018

Privately-held Swiss b firm Neovii Pharmaceuticals and Mundipharma have entered into an agreement giving Mundipharma the rights to develop and distribute its polyclonal antibody immunosuppressant Grafalon (anti T-lymphocyte immunoglobulin), in China and Japan from end October.

Grafalon is indicated in solid organ transplant for prevention and treatment of acute rejection, graft-vs-host disease (GvHD) in stem cell transplant (SCT) and in the treatment of aplastic anemia. Grafalon is the recognised standard of care in leading transplant centers.

Under its license, Mundipharma intends to strengthen the distribution and support of Grafalon in these key markets to advance the clinical development for the prevention of chronic GvHD in SCT. Financial terms of the collaboration have not been disclosed.

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