More positive data for Kymriah in pediatric leukemia

1 February 2018

New data on the first ever CAR T-cell therapy Kymriah (tisagenlecleucel) has been released by Swiss drugmaker Novartis (NOVN: VX).

The analysis of certain patients with B-cell acute lymphoblastic leukemia shows an overall remission rate of 81%, with 60% achieving complete remission. Median follow-up was 13.1 months.

The data, which relate to 75 patients with three or more months of follow-up in the pivotal Phase II ELIANA trial, have been published in The New England Journal of Medicine.

In December Novartis presented six-month data from the JULIET trial which showed sustained complete responses at six months in adults with difficult-to-treat large B-cell lymphoma (DLBCL).

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