Mixed results for Moderna's seasonal flu jab
Shares of Moderna (Nasdaq: MRNA) were down 5.6% at $162.59 after it released new data on its trial of mRNA-1010, that fell short of the already approved vaccines against strains of the less-common influenza B.
The company announced interim results from its pivotal Phase III safety and immunogenicity trial of mRNA-1010 (P301), an mRNA-based seasonal influenza (flu) vaccine candidate, in adults.
These indicated that mRNA-1010 achieved superiority on seroconversion rates for A/H3N2 and A/H1N1, as well as superiority on geometric mean titer ratios for A/H3N2 and non-inferiority on geometric mean titer ratios for A/H1N1. However, non-inferiority was not met for either endpoints for the influenza B/Victoria- and B/Yamagata-lineage strains.
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