Mixed news on PTC's global PIVOT-HD trial for PTC518

19 October 2022
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New Jersey, USA-based rare disease drug developer PTC Therapeutics (Nasdaq: PTCT) saw its shares close down 11% yesterday and fall a further almost 12% to $43.00 pre-market today, after it revealed it has paused US enrollment in a Phase II study of PTC518 in Huntington's disease.

Putting a positive spin on the program in a press release, PTC confirmed that enrollment is active and ongoing for its Phase II PIVOT-HD trial of PTC518 for the treatment of Huntington's disease at study sites globally. To date, PTC has received approval for conduct of the planned 12-month study in several European countries as well as Australia.

Clinical hold in all but name

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