Mixed findings from ICER on targeted immune modulators for RA

13 March 2017

The USA’s Institute for Clinical and Economic Review (ICER) has released an Evidence Report assessing the comparative clinical effectiveness and value of targeted immunomodulatory drugs for the treatment of rheumatoid arthritis (RA).

This Evidence Report will be the subject of the upcoming public meeting of the New England Comparative Effectiveness Public Advisory Council (New England CEPAC) on March 24, 2017.

The medicines cost-effectiveness body’ report evaluates the evidence on targeted immune modulators (TIMs), used alone or in combination with conventional disease-modifying anti-rheumatic drugs (DMARDs), as compared to conventional DMARDs alone. The review also includes an evaluation of two agents currently under regulatory review for this indication: sarilumab (Kevzara, from Sanofi [Euronext: SAN] and Regeneron [Nasdaq: REGN]) and baricitinib (Olumiant, from Eli Lilly [NYSE: LLY]).

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