Miss for Merck’s favezelimab combo in colorectal cancer

26 September 2024

US pharma major Merck (NYSE: MRK) has announced that its Phase III KEYFORM-007 trial did not meet its primary endpoint.

The study was designed to test a combination of favezelimab and Keytruda (pembrolizumab), but did not meet its goal of improving overall survival for people with metastatic colorectal cancer.

The study compared the combination against standard therapies such as regorafenib or trifluridine/tipiracil hydrochloride (TAS-102).

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