Mirati makes gains on adagrasib ESMO data

20 September 2021

US oncology specialist Mirati Therapeutics (Nasdaq: MRTX) was trading 8% higher in early pre-market trading on Monday after presenting results at the European Society for Medical Oncology (ESMO) Congress 2021.

The company announced results from a cohort of the Phase I/II KRYSTAL–1 study evaluating adagrasib at the 600mg BID dose as both monotherapy and in combination with cetuximab in patients with heavily pre-treated colorectal cancer harboring a KRASG12C mutation.

"The results presented at ESMO support further study of adagrasib in KRAS-mutated colon cancer"Results showed that adagrasib alone and with cetuximab demonstrated significant clinical activity and broad disease control in these patients.

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