Mid-stage trial stopped early due to 'overwhelming' effect

18 September 2023

A novel antibody developed by Anthos Therapeutics, a cardiovascular specialist founded by Blackstone Life Sciences, has performed well in a Phase II trial.

Abelacimab is a novel monoclonal antibody under development for people with atrial fibrillation. The therapy locks Factor XI in the inactive state, resulting in dual inhibitory activity.

Scientists at the company believe this approach may provide an effective treatment strategy for a certain group of people who can benefit from the protection of an anticoagulant.

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