Markets respond warmly to positive Phase I Celldex data

13 July 2021

Shares in New Jersey, USA-based Celldex Therapeutics (Nasdaq: CLDX) leapt by a quarter on Monday, after the firm announced positive results from an ongoing Phase Ib trial of CDX-0159.

The firm is trialling the biologic in patients with antihistamine refractory cold urticaria and symptomatic dermographism, the two most common forms of chronic inducible urticaria.

Celldex is exploring a novel mechanism of action, a mast cell depleting approach, which it believes can provide insights into other therapeutic areas, where they may be implicated in the pathology of certain diseases.

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