Low uptake prompts AstraZeneca to withdraw Lumoxiti from US market

13 January 2023

AstraZeneca (LSE: AZN) is to pull its leukemia antibody-drug conjugate Lumoxiti (moxetumomab pasudotox-tdfk) from the US market later this year.

Poor sales performance of the CD22-directed immunotoxin drug, rather than any issues with safety, has been cited by the Anglo-Swedish pharma major as the reason for the move.

Lumoxiti was approved by the US Food and Drug Administration in 2018 to treat patients with relapsed or refractory hairy cell leukemia who have received at least two prior therapies.

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