Low-dose Ampyra fails in multiple sclerosis study, says Acorda

15 August 2012

USA-based biotech firm Acorda Therapeutics (Nasdaq: ACOR) has announced top line results from a post-marketing commitment study evaluating a 5mg dose of Ampyra (dalfampridine-ER) to improve walking in people with multiple sclerosis (MS), showing that the study failed to confirm efficacy of the low dose.

The lower dose of the drug is being investigated as a result of seizures associated with Ampyra treatment, which the US Food and Drug Administration has recently reiterated (The Pharma Letter July 25). Notwithstanding the disappointing results, Acorda’s shares rose 3% to $22.40.

Fears about patent protection

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