Liver injury linked to hep C treatments

29 August 2019

A trio of hepatitis C regimens has been linked to cases of worsening function or failure of the liver.

Those affected are some of those with advanced liver disease taking AbbVie’s (NYSE: ABBV) Mavyret (glecaprevir/pibrentasvir), Merck & Co’s (NYSE: MRK) Zepatier (elbasvir/grazoprevir) or Gilead Sciences’ (Nasdaq: GILD) Vosevi (sofosbuvir/velpatasvir/voxilaprevir).

The US Food and Drug Administration (FDA) has put out a MedWatch safety alert warning of these rare occurrences. The agency identified 63 cases of worsening liver function, or decompensation, among hepatitis C patients taking these regimens.

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